Friday, April 25, 2014

Smoking Cigarettes Helps in Preventing Parkinson Disease


Smoking Cigarettes
About a decade ago researchers discovered that smokers were 60% less likely to develop Parkinson's disease. This disease represents a degenerative disorder of the central nervous system and is quite spread among aged human. Recently a team of Israeli researchers have uncovered the genetic mechanism that protects smokers from this unsettling condition.

The researchers conducted genetic testing on blood samples from 677 Parkinson's patients, 438 of whom were never smokers and 239 who are currently are or had been smokers in some during a period of their life. Preliminary results indicated a link between nicotine dependence and a protective mechanism against the disease. This is reflected in the fact that a cluster of genes known as CHRNB5, CHRNB4 and CHRNB3 became more dependent on nicotine and also held back the development of Parkinson's. This discovery contributes to the perception of the mechanism in nicotine that protects against damage to the brain chemical dopamine, which is linked to the appearance of disease in the first place. While there is no doubt that smoking is bad for your health, the finding allows for the detection of new approaches for Parkinson's therapies, such as medications that imitate the chemical impact of nicotine in human brain.




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